Used primarily as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Its sulfonyl chloride group readily reacts with amines and alcohols, making it valuable for constructing sulfonamides and sulfonate esters—common motifs in drug design. It is especially useful in the development of bioactive molecules where the difluorobenzene moiety enhances metabolic stability and membrane permeability. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to the electronic and steric influence of the fluorine atoms. Also utilized in the preparation of functionalized polymers and specialty materials requiring thermal and chemical resistance.