Used primarily as a reagent in organic synthesis, particularly in the preparation of sulfonamides and sulfonate esters. It serves as a sulfonylating agent in pharmaceutical manufacturing, where it introduces the bromomethanesulfonyl group to amines or alcohols. This compound is also employed in the development of agrochemicals and functional materials due to its reactivity with nucleophiles. Its role in peptide chemistry includes modifying amino acid side chains for research purposes. Handling requires caution due to its lachrymatory and corrosive properties.