4-Bromo-2-(Trifluoromethyl)Benzenesulfonyl Chloride
≥98%
Reagent
Code: #147081
CAS Number
176225-10-8
blur_circular Chemical Specifications
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Molecular Information
Weight
323.51 g/mol
Formula
C₇H₃BrClF₃O₂S
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Registry Numbers
MDL Number
MFCD03094392
thermostat
Physical Properties
Melting Point
54-58 °C
Boiling Point
285.6ºC
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Storage & Handling
Density
1.84g/cm3
Storage
2-8°C, dry
description Product Description
Used primarily as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its reactive sulfonyl chloride group enables the formation of sulfonamides, which are common structural motifs in bioactive molecules. It is particularly valuable in the development of herbicides and fungicides due to the electron-withdrawing trifluoromethyl and bromo substituents enhancing stability and target binding. Also employed in medicinal chemistry for constructing kinase inhibitors and other enzyme modulators. The compound’s halogen atoms allow further functionalization via cross-coupling reactions, expanding its utility in drug discovery and materials science.
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