Used primarily as a fluorinated sulfonyl chloride reagent in organic synthesis, particularly in the preparation of sulfonate esters and sulfonamides with enhanced lipophilicity and metabolic stability. Its trifluoroethoxy groups contribute to increased electron-withdrawing properties, making it valuable in the development of pharmaceuticals and agrochemicals where fluorine substitution improves bioavailability and resistance to degradation. Commonly employed in the synthesis of protease inhibitors and other biologically active compounds requiring high chemical stability. Also utilized in materials science for modifying polymer surfaces to improve hydrophobicity and chemical resistance.