3,3-Difluoropyrrolidine-1-sulfonyl chloride

95%

Reagent Code: #131544
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CAS Number 1187160-31-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 205.61 g/mol
Formula C₄H₆ClF₂NO₂S
badge Registry Numbers
MDL Number MFCD27918725
thermostat Physical Properties
Boiling Point 260.7±40.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.63±0.1 g/cm3(Predicted)
Storage 2-8°C, Sealed, Inert Gas

description Product Description

Used as a key intermediate in the synthesis of biologically active compounds, particularly in pharmaceuticals and agrochemicals. Its structure enables the introduction of a difluorinated pyrrolidine moiety, which can enhance metabolic stability, membrane permeability, and binding affinity in drug molecules. Commonly employed in the development of protease inhibitors and kinase inhibitors due to its ability to mimic peptide bonds and influence conformational rigidity. Also utilized in the preparation of sulfonamide derivatives through reactions with amines, enabling the expansion of chemical diversity in medicinal chemistry research.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿15,450.00
inventory 250mg
10-20 days ฿26,250.00

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