Naphthalen-2-ylmethanesulfonyl chloride
95%
Reagent
Code: #130331
CAS Number
161448-78-8
blur_circular Chemical Specifications
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Molecular Information
Weight
240.71 g/mol
Formula
C₁₁H₉ClO₂S
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Registry Numbers
MDL Number
MFCD10697742
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Physical Properties
Boiling Point
395.5±21.0 °C(Predicted)
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Storage & Handling
Density
1.397±0.06 g/cm3(Predicted)
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used primarily as a sulfonylating agent in organic synthesis, enabling the introduction of the naphthalen-2-ylmethylsulfonyl group to various nucleophiles such as amines and alcohols. This modification is valuable in the development of pharmaceuticals and agrochemicals, where sulfonyl derivatives often enhance biological activity or metabolic stability. It serves as an intermediate in the preparation of sulfonamides, which are common motifs in drug design due to their role as enzyme inhibitors. Its aromatic and sulfonyl functionalities make it suitable for constructing complex molecules in medicinal chemistry research.
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