Quinoxaline-5-sulfonyl chloride is primarily used as a versatile intermediate in organic synthesis, particularly in the preparation of sulfonamide derivatives. These derivatives are valuable in the development of pharmaceuticals, including antibiotics and antiviral agents, due to their biological activity. The compound is also employed in the creation of dyes and pigments, where its sulfonyl chloride group facilitates the introduction of sulfonamide linkages into complex molecules. Additionally, it finds application in materials science for the modification of polymers and surfaces, enhancing their properties for specific industrial uses. Its reactivity makes it a key reagent in research and development for synthesizing novel compounds with potential applications in various fields.