Used primarily as a reagent in organic synthesis, this compound is valuable for introducing the 3,4,5-trimethoxybenzenesulfonyl group into target molecules. It is commonly employed in the preparation of sulfonamides, which are important in pharmaceutical research for developing drugs with antibacterial, antiviral, or anticancer properties. Additionally, it serves as a key intermediate in the synthesis of complex organic compounds, particularly in the fields of medicinal chemistry and materials science. Its reactivity with amines and alcohols makes it useful for creating sulfonate esters and other derivatives, which can be further modified for various applications.