Used extensively in organic synthesis, particularly as a reagent for introducing sulfonamide groups into molecules. It plays a crucial role in the preparation of sulfonamides, which are valuable in pharmaceutical applications, including the development of antibiotics and other therapeutic agents. Additionally, it is employed in the modification of peptides and proteins, aiding in the study of their structure and function. Its reactivity with amines makes it a versatile tool in the creation of diverse chemical compounds for research and industrial purposes.