Primarily used in organic synthesis, this chemical serves as a key reagent for introducing the naphthalenesulfonyl group into various molecules. It is widely employed in the preparation of sulfonamides, which are valuable in pharmaceutical research for developing drugs with antibacterial, antiviral, or anti-inflammatory properties. Additionally, it is utilized in peptide chemistry to protect amino groups during synthesis, ensuring selective reactions. In material science, it aids in modifying polymers and creating specialized coatings. Its reactivity with amines and alcohols makes it a versatile tool in constructing complex organic compounds for industrial and laboratory applications.