Used primarily as an alkylating agent in organic synthesis, enabling the introduction of the 2,2-difluoroethyl group to various substrates. Its reactivity makes it valuable in pharmaceutical development, where fluorinated moieties can enhance metabolic stability, bioavailability, and binding affinity of drug candidates. Commonly employed in the preparation of fluorinated analogs of bioactive molecules, especially in medicinal chemistry research targeting central nervous system agents, enzyme inhibitors, and imaging probes. Due to the presence of fluorine atoms, compounds derived from this reagent often exhibit improved lipophilicity and membrane permeability. Handle with care—highly reactive and potentially hazardous.