N-tert-Butyl-4-fluorobenzenesulfonamide
97%
science Other reagents with same CAS 29083-05-4
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description Product Description
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of sulfonamide-based drugs with antimicrobial, anti-inflammatory, and antidiabetic properties. It serves as a building block in agrochemicals for creating herbicides and plant growth regulators due to its stability and reactivity. The fluorinated aromatic ring enhances membrane permeability in bioactive molecules, making it valuable in medicinal chemistry for optimizing drug potency. Also employed in research for designing enzyme inhibitors, especially in protease and kinase-targeted therapies. Its tert-butyl group contributes to steric hindrance, improving metabolic stability in drug candidates. Additionally, it functions as a protecting group for the sulfonamide nitrogen in selective organic synthesis, as the tert-butyl moiety is stable and removable under mild acidic conditions.
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