4-(fluorosulfonyl)benzoic acid
98%
Reagent
Code: #188223
CAS Number
455-26-5
blur_circular Chemical Specifications
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Molecular Information
Weight
204.1756 g/mol
Formula
C₇H₅FO₄S
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Registry Numbers
MDL Number
MFCD00007420
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Physical Properties
Melting Point
272-273 ℃(lit.)
Boiling Point
335.3 ℃ at 760mmHg
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Storage & Handling
Storage
Room temperature, sealed, dry, inert gas
description Product Description
Used primarily as a key intermediate in the synthesis of sulfonamide-based pharmaceuticals and agrochemicals. Its fluorosulfonyl group is highly reactive, enabling efficient sulfonamide bond formation through nucleophilic substitution. Commonly employed in the preparation of bioactive molecules, including protease inhibitors and anti-inflammatory agents. Also utilized in materials science for modifying polymers to enhance thermal stability and chemical resistance. Its reactivity makes it valuable in click chemistry applications, particularly in developing fluorinated compounds for medicinal chemistry research.
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