4-Acetamidobenzenesulfonamide, commonly known as sulfacetamide, is a sulfonamide antibiotic primarily used in topical formulations for treating bacterial infections such as conjunctivitis, acne, and seborrheic dermatitis. It functions as a key agent in medicinal chemistry by inhibiting bacterial growth through interference with folic acid synthesis. This compound also serves as an intermediate in the synthesis of other sulfonamide antibiotics and antimicrobial agents. In research settings, it is employed for preparing derivatives exhibiting potential biological activities, including anti-inflammatory properties. Its sulfonamide structure is valuable for designing compounds that target enzyme systems in pathogenic organisms.