2-Bromo-3-Methylpyridine 1-Oxide
95%
Reagent
Code: #150393
CAS Number
19230-57-0
blur_circular Chemical Specifications
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Molecular Information
Weight
188.02 g/mol
Formula
C₆H₆BrNO
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Registry Numbers
MDL Number
MFCD20270297
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Storage & Handling
Storage
Room temperature, inert atmosphere
description Product Description
Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of nicotinic receptor agonists and antagonists. It serves as a building block in the preparation of bioactive molecules due to the presence of both bromine and the pyridine N-oxide functionality, which allow for selective functionalization through cross-coupling reactions and directed ortho-metalation. Commonly employed in agrochemical research for designing novel pesticides and in medicinal chemistry for constructing complex heterocyclic systems. The N-oxide group enhances solubility and can act as a directing group in metal-catalyzed reactions, improving regioselectivity during derivatization.
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