1-(Diphenylmethyl)-3,3-difluoroazetidine
97%
Reagent
Code: #167395
CAS Number
288315-02-6
blur_circular Chemical Specifications
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Molecular Information
Weight
259.29 g/mol
Formula
C₁₆H₁₅F₂N
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Registry Numbers
MDL Number
MFCD09264457
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Physical Properties
Boiling Point
311.7±42.0 °C(Predicted)
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Storage & Handling
Density
1.20±0.1 g/cm3(Predicted)
Storage
2-8°C
description Product Description
Used primarily in pharmaceutical research as a key intermediate in the synthesis of bioactive molecules. Its structure supports the development of compounds with central nervous system activity, particularly in the design of histamine H3 receptor antagonists. The diphenylmethyl group enhances lipophilicity and blood-brain barrier penetration, making it valuable in neuropharmacology. Additionally, the difluoroazetidine moiety contributes to metabolic stability and improved pharmacokinetic profiles in drug candidates. It is also explored in the development of enzyme inhibitors and receptor modulators for treating neurological disorders such as narcolepsy, epilepsy, and cognitive impairments.
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