tert-Butyl (R)-3-(piperidin-3-yl)azetidine-1-carboxylate
98%
Reagent
Code: #149955
CAS Number
2174940-65-7
blur_circular Chemical Specifications
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Molecular Information
Weight
240.34 g/mol
Formula
C₁₃H₂₄N₂O₂
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors and central nervous system (CNS) active compounds. Its structure supports selective binding in biological targets due to the presence of a chiral center and constrained ring systems. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies, especially in optimizing drug candidates for improved metabolic stability and bioavailability. The tert-butyl carbamate (Boc) group enables easy protection of the amine during peptide coupling or multistep synthesis, making it valuable in solid-phase and solution-phase drug discovery.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | Light Yellow Solid |
| Purity (%) | 97.5-100% |
| Specific rotation [a]20/D (C=1, DMF (50 vol%)) | 2.92-8.92 |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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