1-Boc-3-hydroxyazetidine
97%
Reagent
Code: #143361
Alias
1-(tert-butoxycarbonyl)-3-hydroxyazetidine, N-Boc-3-hydroxyazetidine
CAS Number
141699-55-0
blur_circular Chemical Specifications
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Molecular Information
Weight
173.21 g/mol
Formula
C₈H₁₅NO₃
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Registry Numbers
MDL Number
MFCD04115305
thermostat
Physical Properties
Melting Point
42-44°C
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of biologically active molecules targeting central nervous system disorders and metabolic diseases. Its protected azetidine ring with a hydroxyl functional group allows for selective modifications in multi-step syntheses, making it valuable in medicinal chemistry for building complex heterocyclic structures. Commonly employed in the preparation of kinase inhibitors and GPCR modulators due to the azetidine scaffold’s favorable pharmacokinetic properties.
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