H-151 is primarily used in research settings to study the STING (Stimulator of Interferon Genes) pathway, which plays a critical role in the immune response. It acts as a potent and selective inhibitor of STING, making it a valuable tool for understanding the mechanisms of inflammation, autoimmune diseases, and cancer. Researchers utilize H-151 to investigate how blocking STING signaling affects immune system activation and to explore potential therapeutic strategies for conditions where STING activity is dysregulated. Its application extends to preclinical studies aimed at developing treatments for diseases linked to overactive STING pathways, such as certain inflammatory disorders and cancers.