Dexamethasone palmitate is primarily used in medical applications as an anti-inflammatory and immunosuppressive agent. It is particularly effective in treating conditions involving inflammation, such as arthritis, allergic reactions, and certain skin disorders. The palmitate ester form enhances its lipophilicity, allowing for better absorption and prolonged action when administered topically or via injection. In dermatology, it is often utilized in creams or ointments to reduce swelling, redness, and itching associated with various skin conditions. Additionally, it is employed in ophthalmic formulations to manage eye inflammation and in joint injections to alleviate pain and inflammation in conditions like rheumatoid arthritis. Its extended-release properties make it a suitable option for long-term management of chronic inflammatory diseases.