Sodium prasterone sulfate is primarily used in the medical field for its role in hormone replacement therapy, particularly in addressing symptoms associated with menopause. It helps in alleviating conditions like vaginal atrophy, which can cause discomfort, dryness, and pain during intercourse. By converting into active hormones within the body, it supports the restoration of healthy vaginal tissue and improves overall quality of life for postmenopausal women. Additionally, it has been explored for its potential in treating other hormone-related conditions, though its primary application remains focused on menopausal symptom management.