PluriSln1 is primarily utilized in the field of stem cell research and regenerative medicine. It plays a crucial role in the selective inhibition of human pluripotent stem cells, aiding in the elimination of undifferentiated cells from differentiated cell populations. This is particularly important in ensuring the safety and efficacy of stem cell-based therapies, as residual undifferentiated cells can lead to tumor formation. Additionally, PluriSln1 is employed in laboratory settings to study cell differentiation mechanisms and to develop more refined protocols for generating specific cell types from pluripotent stem cells. Its application is also being explored in cancer research, where it helps in understanding and targeting cancer stem cells, which are often resistant to conventional treatments.