Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of neuroactive agents targeting the central nervous system. Its spirocyclic structure and ethynyl functional group make it valuable for constructing complex molecular frameworks in medicinal chemistry. Commonly employed in research settings to build modulators of ion channels and receptors, especially GABA and NMDA receptor ligands. The tert-butyl carboxylate group allows for easy deprotection and further derivatization, enabling efficient route optimization in drug discovery programs. Also utilized in the preparation of analogs for structure-activity relationship (SAR) studies due to its conformational rigidity and metabolic stability.