tert-Butyl 3,3-difluoro-1,8-diazaspiro[4.5]decane-8-carboxylate

95%

Reagent Code: #150459
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CAS Number 1250999-05-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 276.32 g/mol
Formula C₁₃H₂₂F₂N₂O₂
badge Registry Numbers
MDL Number MFCD17016148
thermostat Physical Properties
Boiling Point 340.7±42.0 °C at 760 mmHg
inventory_2 Storage & Handling
Storage -20°C, sealed, light-proof, inert gas

description Product Description

Used as an intermediate in pharmaceutical synthesis, particularly in the development of bioactive molecules targeting central nervous system disorders. Its spirocyclic structure with fluorinated substituents enhances metabolic stability and blood-brain barrier penetration, making it valuable in medicinal chemistry. The tert-butoxycarbonyl (Boc) protecting group allows for selective amine functionalization during multi-step synthesis. Commonly employed in the preparation of kinase inhibitors and GPCR modulators due to its favorable conformational rigidity and polarity profile.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿35,710.00
inventory 250mg
10-20 days ฿67,210.00

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