2-Azaspiro[4.5]decane hydrochloride is primarily utilized in pharmaceutical research and development as a key intermediate in the synthesis of various bioactive compounds. Its spirocyclic structure makes it a valuable building block for creating molecules with potential therapeutic applications, particularly in the development of central nervous system (CNS) drugs. It is often employed in the design of ligands for neurotransmitter receptors, contributing to the study of neurological disorders such as depression, anxiety, and schizophrenia. Additionally, its chemical framework is explored in the creation of novel drug candidates targeting pain management and neurodegenerative diseases. The compound’s versatility and stability also make it useful in medicinal chemistry for optimizing drug properties like bioavailability and metabolic stability.