Used as a key intermediate in the synthesis of biologically active compounds, particularly in pharmaceuticals targeting central nervous system disorders. Its rigid spirocyclic structure and polar sulfone group make it valuable for enhancing metabolic stability and binding selectivity in drug candidates. Employed in medicinal chemistry to construct constrained analogs of gamma-aminobutyric acid (GABA) and other neurotransmitters. Also applied in the development of novel enzyme inhibitors due to its ability to mimic transition states in biochemical reactions.