Used in the synthesis of complex organic molecules, particularly in pharmaceutical research for developing protease inhibitors. Its functional groups and stereochemistry make it valuable as an intermediate in asymmetric synthesis. The silyl protecting groups allow selective deprotection and further derivatization, enabling stepwise construction of bioactive compounds. Commonly applied in the development of antiviral agents, especially in the total synthesis of hepatitis C virus (HCV) NS3/4A protease inhibitors. Its spirocyclic structure contributes to conformational rigidity, enhancing target selectivity in drug design.