Used in pharmaceutical research as a key intermediate in the synthesis of kinase inhibitors, particularly for targeting cancer-related enzymes such as PI3K and mTOR. Its spirocyclic structure enhances binding selectivity and metabolic stability, making it valuable in developing targeted therapies. Also explored in the design of anti-inflammatory and neuroprotective agents due to its ability to cross the blood-brain barrier. Commonly modified to improve solubility and bioavailability in drug candidates.