3H-Spiro[isobenzofuran-1,3'-piperidin]-3-one
≥97%
Reagent
Code: #195888
CAS Number
189321-67-3
science Other reagents with same CAS 189321-67-3
blur_circular Chemical Specifications
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Molecular Information
Weight
203.24 g/mol
Formula
C₁₂H₁₃NO₂
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Registry Numbers
MDL Number
MFCD11616038
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Physical Properties
Boiling Point
411 °C at 760 mmHg
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Storage & Handling
Storage
2-8°C, dry, sealed
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of central nervous system (CNS) active compounds. Its spirocyclic structure provides conformational rigidity, making it valuable in drug design for enhancing selectivity and metabolic stability. It is employed in the preparation of potent serotonin and dopamine receptor modulators, which are relevant for treating psychiatric and neurological disorders such as depression, schizophrenia, and Parkinson’s disease. Additionally, derivatives of this compound have shown potential in pain management therapies due to their interaction with opioid receptors. Its application in medicinal chemistry supports the exploration of novel bioactive molecules with improved pharmacokinetic profiles.
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