(2H,4H-Spiro[benzo[b][1,4]dioxepine-3,1'-cyclopropan]-6-yl)boronic acid
97%
Reagent
Code: #192590
CAS Number
2096335-53-2
science Other reagents with same CAS 2096335-53-2
blur_circular Chemical Specifications
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Molecular Information
Weight
220.03 g/mol
Formula
C₁₁H₁₃BO₄
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Registry Numbers
MDL Number
MFCD20441817
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Physical Properties
Boiling Point
420.9±55.0 °C(Predicted)
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Storage & Handling
Density
1.34±0.1 g/cm3(Predicted)
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used in organic synthesis as a boronic acid coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds for constructing biaryl and heterobiaryl systems. Its spirocyclic structure with a fused dioxepine and cyclopropane ring enhances structural rigidity, making it valuable in medicinal chemistry for developing bioactive molecules. The compound is particularly useful in drug discovery for creating analogs with improved metabolic stability and target selectivity. It also serves as an intermediate in the synthesis of functional materials and pharmaceuticals where constrained geometry influences biological activity.
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