Used in pharmaceutical research as a key intermediate in the synthesis of bioactive compounds targeting central nervous system disorders. Shows potential in the development of novel therapeutics for anxiety and depression due to its structural affinity for neurotransmitter receptors. Also employed in structure-activity relationship (SAR) studies to optimize potency and selectivity in drug candidates. Its spirocyclic framework enhances metabolic stability, making it valuable in designing orally active agents. Investigated for use in PET imaging probes owing to its ability to cross the blood-brain barrier.