tert-Butyl 5-fluorospiro[indoline-3,4'-piperidine]-1'-carboxylate
96%
Reagent
Code: #146613
CAS Number
167484-91-5
blur_circular Chemical Specifications
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Molecular Information
Weight
306.38 g/mol
Formula
C₁₇H₂₃FN₂O₂
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Registry Numbers
MDL Number
MFCD12198573
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and central nervous system (CNS) agents. Its spirocyclic structure provides conformational rigidity, enhancing selectivity and metabolic stability in drug candidates. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to the fluorinated indoline core, which improves bioavailability and binding affinity. Also utilized in the preparation of peptidomimetics and as a building block for novel psychotherapeutic and neurodegenerative disease treatments.
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