2-Azaadamantane-N-oxyl (AZADO) is a stable nitroxyl free radical with diverse applications in research and industry. It is primarily recognized as an efficient organocatalyst for the aerobic oxidation of alcohols to aldehydes and ketones in organic synthesis, offering superior performance compared to traditional catalysts like TEMPO. Additionally, it serves as a spin label in electron paramagnetic resonance (EPR) spectroscopy, facilitating the study of molecular dynamics, structural changes, and interactions in biological systems, polymers, and materials science. Its unique adamantane structure provides exceptional stability, making it ideal for probing mobility in complex molecules. AZADO is also utilized as a radical mediator or initiator in controlled radical polymerization reactions, aiding the development of advanced materials. Furthermore, its role in investigating oxidative stress, redox processes, and electron transfer mechanisms underscores its importance in biochemical, medical, and pharmacological research, including the development of new bioactive compounds.