HC-056456 is primarily used in research settings as a selective antagonist for the S1P1 receptor. This receptor plays a significant role in regulating immune cell trafficking, making HC-056456 valuable in studies focused on autoimmune diseases, inflammation, and immune system modulation. Researchers utilize it to investigate the pathways and mechanisms involved in conditions such as multiple sclerosis, rheumatoid arthritis, and other inflammatory disorders. Additionally, it aids in understanding the role of S1P1 in vascular and lymphatic systems, contributing to potential therapeutic developments. Its application is largely confined to preclinical studies, where it helps elucidate the biological functions of S1P1 and its implications in disease pathology.