C16 (2'(S)-hydroxy) Ceramide (d18:1/16:0) is primarily used in research related to skin biology and dermatology. Its application is significant in studying the role of ceramides in maintaining the skin barrier function. This compound helps in understanding how ceramides contribute to skin hydration and protection against environmental stressors. It is also utilized in the development of skincare products aimed at improving skin health, particularly for conditions like eczema and psoriasis. Additionally, it serves as a reference standard in lipidomics studies to analyze and quantify ceramide levels in biological samples.