ML355 is a potent and selective inhibitor of 12-lipoxygenase (12-LOX), an enzyme critical in the biosynthesis of pro-inflammatory and pro-thrombotic lipid mediators derived from arachidonic acid. It is primarily utilized in pharmacological research to study and mitigate inflammation, oxidative stress, and related pathologies, particularly in neurodegenerative diseases such as Alzheimer's disease and other conditions involving chronic neuroinflammation. By inhibiting 12-LOX, ML355 reduces the production of harmful lipid peroxides and neurotoxic species, thereby protecting neuronal cells from damage and potentially slowing disease progression. This compound holds promise for developing novel therapeutics targeting inflammation-driven neurological disorders, with ongoing preclinical investigations assessing its efficacy and safety.