Rink Amide AM resin is widely used in solid-phase peptide synthesis (SPPS) as a versatile support material. It is particularly valuable for synthesizing C-terminal amidated peptides, which are common in biologically active compounds. The resin facilitates the attachment of the first amino acid through its amide linker, allowing for the stepwise addition of subsequent amino acids. After synthesis, the peptide can be cleaved from the resin while retaining the amide group at the C-terminus. This makes it a preferred choice for producing peptides used in pharmaceutical research, drug development, and biochemical studies. Its compatibility with Fmoc (fluorenylmethyloxycarbonyl) chemistry further enhances its utility in automated peptide synthesizers.