(Cyclohexylidenemethoxy)(trimethyl)silane
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Used primarily as a silyl protecting group reagent in organic synthesis, particularly for the protection of alcohols and phenols. Its cyclohexylidene backbone provides steric bulk, enhancing selectivity in reactions where control over functional group reactivity is critical. Commonly employed in multi-step syntheses of complex natural products and pharmaceuticals, it helps mask reactive hydroxyl groups under basic or nucleophilic conditions. The group can be removed under mild acidic conditions, allowing for deprotection without damaging sensitive molecular frameworks. Its stability under a range of reaction conditions makes it valuable in the synthesis of peptides, carbohydrates, and heterocyclic compounds.
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