tert-Butyldimethylsilane is an organosilicon compound widely used in organic synthesis as a reagent for hydrosilylation reactions, adding across carbon-carbon multiple bonds in the presence of transition metal catalysts to form new C-Si bonds. It also functions as a hydrogen atom donor in radical-mediated processes, such as deoxygenations and reductions, including variants of the Barton-McCombie reaction. Additionally, it serves as a precursor in the synthesis of silicon-based materials, silyl ethers, and other silane derivatives. Its selective reactivity and stability under mild conditions make it valuable for constructing complex molecules in pharmaceutical and materials chemistry.