2-(t-Butyldimethylsilyloxy)ethanamine is a protected derivative of ethanolamine, where the hydroxyl group is shielded by the t-butyldimethylsilyl (TBDMS) protecting group, leaving the primary amine free. It serves as a versatile building block in organic synthesis for constructing complex molecules, including pharmaceuticals, natural products, and peptides. The TBDMS protection prevents interference from the hydroxyl during reactions at the amine or other functional groups, enabling selective transformations. The protecting group is readily removed under mild acidic or fluoride conditions to reveal the free hydroxyl. This reagent is prized for its stability across diverse reaction conditions and broad compatibility with common synthetic reagents.