Bis(t-butyldimethylsiloxy)ethane is primarily utilized in organic synthesis as a protecting group for diols, particularly in the preparation of complex molecules such as natural products and pharmaceuticals. Its application is crucial in multi-step synthesis processes where selective protection and deprotection of hydroxyl groups are required. This compound is also employed in the synthesis of silicon-based polymers and materials, where it acts as a cross-linking agent or a precursor. Additionally, it finds use in the field of surface chemistry for modifying surfaces to impart specific properties like hydrophobicity or chemical resistance. Its stability under various reaction conditions makes it a valuable reagent in advanced chemical research and industrial applications.