O-(tert-Butyldiphenylsilyl)hydroxylamine is widely used in organic synthesis as a protecting group for hydroxylamines. It is particularly valuable in the preparation of complex molecules, where selective protection and deprotection of functional groups are necessary. This compound is often employed in the synthesis of pharmaceuticals, agrochemicals, and natural products, where it helps to stabilize reactive intermediates and prevent unwanted side reactions. Additionally, it is utilized in the development of novel chemical reactions and methodologies, contributing to advancements in synthetic chemistry. Its ability to be easily removed under mild conditions makes it a versatile tool in multi-step synthetic processes.