(2S)-2-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]diphenylmethyl]pyrrolidine
≥98%,99%e.e.
blur_circular Chemical Specifications
description Product Description
This compound, known as the tert-butyldimethylsilyl (TBDMS) ether of (S)-α,α-diphenylprolinol, is a chiral organocatalyst widely used in asymmetric synthesis. It facilitates enantioselective reactions such as Michael additions, aldol reactions, and Mannich-type processes, enabling the formation of C-C and C-N bonds with high stereocontrol. Its sterically hindered structure promotes iminium or enamine activation mechanisms, making it invaluable in the synthesis of pharmaceuticals, natural products, and complex chiral molecules. The catalyst's stability under diverse conditions supports multi-step synthetic sequences, and it is particularly effective in the preparation of enantiopure intermediates for drug development.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | White to light yellow powder, fine crystals with lumps |
| Purity | 97.5-100 |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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