1-(tert-Butyldimethylsilyoxy)-2-propanone
≥95%
Reagent
Code: #63830
CAS Number
74685-00-0
blur_circular Chemical Specifications
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Molecular Information
Weight
188.34 g/mol
Formula
C₉H₂₀O₂Si
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Registry Numbers
MDL Number
MFCD01321330
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Physical Properties
Boiling Point
35-38 °C at 0.6 mmHg (lit.)
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Storage & Handling
Density
0.976 g/cm3 at 25 °C (lit.)
Storage
2-8°C, dry, sealed
description Product Description
This compound, 1-(tert-Butyldimethylsilyloxy)-2-propanone, is a protected derivative of hydroxyacetone featuring a tert-butyldimethylsilyl (TBDMS) group on the hydroxyl functionality. It serves as a key intermediate in organic synthesis, enabling selective manipulation of the ketone group while the alcohol remains protected. This is particularly useful in the preparation of pharmaceuticals, natural products, and fine chemicals, where precise control over functional groups is essential. The TBDMS moiety provides stability across a range of reaction conditions, supporting efficient multi-step processes and the assembly of complex molecular structures.
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