5-(((tert-Butyldimethylsilyl)oxy)methyl)-5-phenylimidazolidine-2, 4-dione

95%

Reagent Code: #63717
fingerprint
CAS Number 1401226-49-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 320.46 g/mol
Formula C₁₆H₂₄N₂O₃Si
inventory_2 Storage & Handling
Storage room temperature

description Product Description

This compound, 5-(((tert-Butyldimethylsilyl)oxy)methyl)-5-phenylimidazolidine-2,4-dione, serves as a key protected intermediate in organic synthesis, especially for pharmaceutical applications. The imidazolidine-2,4-dione (hydantoin) core features a phenyl group and a hydroxymethyl substituent at the 5-position, where the hydroxyl is protected by the tert-butyldimethylsilyl (TBDMS) group. This silyl ether protection shields the hydroxyl from unwanted reactions during multi-step syntheses, enabling selective transformations of other functional groups. The TBDMS protecting group is stable under a wide range of conditions but can be selectively removed using mild reagents like tetrabutylammonium fluoride (TBAF), restoring the free hydroxyl without affecting the rest of the molecule. Such protected intermediates are essential in the development of complex drugs, agrochemicals, and fine chemicals requiring precise control over reactivity.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿30,600.00
inventory 250mg
10-20 days ฿54,000.00

Cart

No products

Subtotal: 0.00
Total 0.00 THB