(3-Bromopropoxy)-tert-butyldimethylsilane
97%
Reagent
Code: #63682
Alias
3-Bromopropyl tert-butyl dimethyl siloxane
CAS Number
89031-84-5
blur_circular Chemical Specifications
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Molecular Information
Weight
253.25 g/mol
Formula
C₉H₂₁BrOSi
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Registry Numbers
MDL Number
MFCD00216589
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Physical Properties
Boiling Point
182 °C(lit.)
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Storage & Handling
Density
1.093 g/mL at 25 °C(lit.)
Storage
2~8℃, sealed, protected from light
description Product Description
(3-Bromopropoxy)-tert-butyldimethylsilane is a silyl-protected derivative of 3-bromopropan-1-ol, featuring a tert-butyldimethylsilyl (TBDMS) group on the oxygen. This compound serves as a versatile alkylating agent in organic synthesis, where the bromide functionality enables nucleophilic substitution reactions to form carbon-oxygen or carbon-carbon bonds, while the TBDMS protection prevents interference from the hydroxyl group. It is particularly useful as a linker or spacer in multi-step syntheses of complex molecules, such as in pharmaceutical, agrochemical, and materials chemistry. The TBDMS group provides stability under various conditions, allowing selective transformations, and can be deprotected under mild acidic conditions to reveal the free alcohol for further functionalization. This reagent facilitates efficient construction of molecular architectures requiring precise control over reactivity.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Purity (GC) | 97-100 |
| Refractive Index n20D | 1.45-1.454 |
| Specific Gravity (20°C) | 1.09-1.095 |
| Appearance | Colorless liquid |
| Infrared Spectrum | Conforms to Structure |
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