(3-Bromophenoxy)(tert-butyl)dimethylsilane

98%

Reagent Code: #151020
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CAS Number 65423-56-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 287.27 g/mol
Formula C₁₂H₁₉BrOSi
badge Registry Numbers
MDL Number MFCD01318106
inventory_2 Storage & Handling
Density 1.16 g/cm3(Predicted)
Storage 2-8°C, inert atmosphere

description Product Description

(3-Bromophenoxy)(tert-butyl)dimethylsilane is the tert-butyldimethylsilyl (TBDMS)-protected derivative of 3-bromophenol. The silyl ether serves as a protecting group for the phenolic hydroxyl, enabling selective reactions at the aryl bromide position, such as palladium-catalyzed cross-coupling (e.g., Suzuki-Miyaura, Sonogashira). This stability under basic and neutral conditions, with deprotection possible under mild acidic conditions, makes it valuable in multi-step organic synthesis, particularly for pharmaceuticals, agrochemicals, and advanced materials. The bulky TBDMS group provides steric hindrance, minimizing unwanted side reactions during assembly of complex molecules.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿810.00
inventory 5g
10-20 days ฿3,230.00
inventory 25g
10-20 days ฿12,290.00

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