Monodisperse amino silica microspheres are widely used in chromatography as stationary phases due to their uniform size and surface functionality. They enhance separation efficiency and resolution in high-performance liquid chromatography (HPLC) and gas chromatography (GC).

In biomedical applications, these microspheres serve as carriers for drug delivery systems, enabling controlled release and targeted therapy. Their amino groups allow for surface modification and conjugation with biomolecules, making them suitable for biosensors and diagnostic assays.

They are also employed in catalysis as supports for immobilizing enzymes or metal catalysts, improving stability and reusability. Additionally, their use in environmental science includes water purification and pollutant adsorption, where their functionalized surface effectively binds contaminants.

In material science, these microspheres are utilized in coatings and composites to enhance mechanical properties and surface characteristics. Their uniformity and functional groups make them versatile in various industrial and research applications.