Monodisperse amino silica microspheres are widely used in chromatography for the separation and purification of biomolecules such as proteins, peptides, and nucleic acids. Their uniform size and functional amino groups make them ideal for high-resolution separations.

In drug delivery systems, these microspheres serve as carriers for controlled release of therapeutic agents, enhancing drug stability and targeting specific tissues. They are also employed in diagnostics as solid supports for immobilizing enzymes, antibodies, or DNA probes, facilitating sensitive and accurate detection of biomarkers.

Additionally, their amino groups enable surface modification, making them suitable for catalysis, where they act as supports for catalysts in various chemical reactions. Their biocompatibility and functional properties also make them valuable in tissue engineering for scaffolding and cell culture applications.