Used primarily as a coupling agent in surface modification, it enhances adhesion between organic and inorganic materials. Its azide group enables photochemical reactions, making it valuable in photoaffinity labeling for studying biomolecular interactions. In material science, it is applied to functionalize surfaces of glass, silicon, or metals, improving compatibility with polymers or coatings. It also plays a role in immobilizing biomolecules on solid supports for biosensors or diagnostic devices. Additionally, its trimethoxy groups facilitate hydrolysis and condensation, forming stable siloxane bonds with substrates.